Mnemonic for Adrenoceptors location

Adrenergic receptors

First of all, let's talk about adrenergic receptors in brief that what are adrenergic receptors?
So adrenergic receptors are G protein-coupled receptors or also called seven pass receptors upon these receptors the catecholamines or the epinephrine and norepinephrine act which are naturally made inside the body.

there are actually two types of adrenergic receptors both are further divided into two subtypes they are as under;
Alpha 1
Alpha 2
Beta 1
Beta 2

location of adrenergic receptors

Before we talk about the mnemonic for the location of adrenergic receptors Let's first know the exact location of all adrenergic receptors in our body then it will be easy for us to memorize the location of the adrenergic receptors or adrenoceptors.

as adrenergic neurons involve the sympathetic nervous system so during sympathetic stimulation there are some organs that have to be stimulated and some organs which are to be inhibited. For example, if we talk about the heart which has to be stimulated, and detrusor muscles which have to be inhibited in order to stop urination, for example, if a dog is on you and you are running so fast now in this situation you are not going to pee on dog lol. and your muscles must be stimulated.

Now let's come to the mnemonic for adrenergic receptors location.

Mnemonic for adrenergic receptors

to get to know about the actions of adrenergic receptors upon stimulation first you have to know about the actions  of parasympathetic or cholinergic drugs or receptors as adrenergic is wholly solly opposite to it for cholinergic drugs mnemonic click here
so the mnemonic for adrenergic receptors locations will be like in two ways 

• The first one is  all those organs that have to be stimulated will have alpha1 receptors except the Heart, kidney,, and adipocytes or fat cells they will have beta1

• The second one is all those organs to be inhabited will have beta2 except the preganglionic neuron, platelet cells, and insulin-producing cells or beta-cell of the pancreas, they will have alpha2

let's understand this mnemonic after understanding believe me you will exactly the actions of every adrenergic drug also the location of the receptors

about stimulation of organs I mean the contraction of the smooth muscle in blood vessels

and about inhibtion of organs means the relaxation of smooth muscles.

i know its confusing but let me do some examples iam sure you will understand it.

if we talk about the GIT so during sympathetic stimulation so the the blood supply to the GIT is inhbited which mean the smooth muscles in blood vessels to the GIT is constricted which have stopped or decrease blood supply to the GIT so in vessels of GIT there will be Alpha 1 but in GIT in general there will be beta 2.

lets have another example

in eyes we have constrictor pupillae so during sypathetic stimulation they are stimulated and hence dilation of pupil occurs so here will be alpha 1

the sphincters will also have alpha1 as they are constricted mean stimulated.

in this way if you once read your book you will easily get this mnemonic 

And remember the exceptions up there.

Happy learning !